LYMPHOCYTOPENIA
PSEUDO:
Excess EDTA (>4.5mg/mL)
TRUE:
- Acquired:
Acute stress (Trauma, Surgery, Burns, Acute illness)
Acute infection (Legionella pneumophila)
Chronic infections (AIDS, Whipple's disease)
Chronic inflammatory disorders (SLE, Sarcoidosis)
Protein-calorie malnutrition
Corticosteroid therapy and excess
Immunosuppressives (Azarthioprine, Cyclosporine, ATG)
Anticancer chemotherapy, radiotherapy
Renal failure
Malignancies (Advanced carcinomas, Hodgkin lymphoma)
- Inherited:
Reticular dysgenesis
Severe combined immunodeficiency
Wiskott-Aldrich syndrome
Common variable hypogammaglobulinaemia
Ataxia telangiectasia