Haematology Watch

LYMPHOCYTOPENIA


PSEUDO:

     Excess EDTA (>4.5mg/mL)


TRUE:

    - Acquired:

       Acute stress (Trauma, Surgery, Burns, Acute illness)

       Acute infection (Legionella pneumophila)

       Chronic infections (AIDS, Whipple's disease)

       Chronic inflammatory disorders (SLE, Sarcoidosis)

       Protein-calorie malnutrition

       Corticosteroid therapy and excess

       Immunosuppressives (Azarthioprine, Cyclosporine, ATG)

       Anticancer chemotherapy, radiotherapy

       Renal failure

       Malignancies (Advanced carcinomas, Hodgkin lymphoma)

    - Inherited:

       Reticular dysgenesis

       Severe combined immunodeficiency

       Wiskott-Aldrich syndrome

       Common variable hypogammaglobulinaemia

       Ataxia telangiectasia