Haematology Watch

Myelodysplasia

 

 Peripheral Blood Smear:


RBC:

 Nuclear:

 Karyorrhexis

 Multinuclearity

 Nuclear budding

 Megaloblastic change 


 Cytoplasmic:

 Intercytoplasmic bridging

 

 



WBC:

Size:

 Small WBC

 Large WBC


Nuclear:

 Hypolobation

 Irregular hypersegmentation


Cytoplasmic:

 Hypogranularity/Agranularity

 Pseudo Chediak-Higashi syndrome

 Auer rods


Platelets:















 Bone marrow Aspiration Smear:


Erythroblasts:

Nuclear:

 Nuclear hyperlobation

 Megaloblastic change




Cytoplasmic:

 Ring sideroblasts

 PAS positivity

 Vacuolization



Myeloid cells:













Megakaryocytes:

Size:

 Micromegakaryocytes


Nuclear:

 Hypolobation

 Multinuclearity